Fluorescence spectrometer for versatile biophysical analyses
Name of applicant
Daniel Otzen
Institution
Aarhus University
Amount
DKK 254,752
Year
2021
Type of grant
Research Infrastructure
Summary
The project provides support for a Cary Eclipse fluorescence spectrometer for interdisciplinary research in biological, chemical and physical sciences at iNANO, Aarhus University. This instrument will allow us to measure how molecules "talk" with each other and how this affects their structure and stability. Examples include proteins involved in neurodegenerative diseases, development of new biomaterials, membrane proteins involved in cell development, green biosurfactants, nucleic acids in health and disease, origami structures of RNA molecules, measuring protein binding to nanoparticles, formation of drugs in immunotherapy, studies of cellular nanoreactors and intramolecular switches in proteins and RNA.