Visualising real-time intracellular calcium changes in the smooth muscle cells of the artery wall
Name of applicant
Thomas Jepps
Institution
University of Copenhagen
Amount
DKK 547,775
Year
2021
Type of grant
Research Infrastructure
Summary
"My laboratory focus on arterial contractions, which are highly dependent on changes in intracellular calcium. This equipment will allow us to visualise real time changes in intracellular calcium within the muscle cells of the arterial wall, while the artery is maintained with tension under physiological conditions. By monitoring these changes in real time we will elucidate physiological and pathophysiological mechanisms controlling blood flow and blood pressure, including how these mechanisms change in hypertension. "