Safe and sound: High-resolution 4D in vivo imaging of vocal and vital organs
Name of applicant
Coen Elemans
Title
Professor
Institution
University of Southern Denmark
Amount
DKK 2,172,000
Year
2022
Type of grant
Research Infrastructure
Summary
All vital functions - respiration, circulation, and body movement - are dynamic processes. How vital functions are controlled and maintained remains a central question in biological and medicine research. As vital functions occur inside intact living animals, measuring their dynamics needs imaging techniques that penetrate the body without harm at millisecond timescale. This project will install a state-of-the-art ultrasound imaging platform that is capable of both high-resolution (3D) and time-resolved (4D), non-invasive, deep-tissue imaging in living animals. This system enables Danish scientists across disciplines to observe vital functions, reduces the number of animals used for research, and promotes research as diverse as heart and vascular function to motor control of the voice.