Modelling exercise training in a dish to illuminate the molecular basis of exercise’s health benefit
Name of applicant
Lykke Sylow
Title
Associate Professor
Institution
University of Copenhagen
Amount
DKK 627,629
Year
2024
Type of grant
Research Infrastructure
Summary
This project will explore how exercise benefits our health. We will use a muscle contraction tool to simulate exercise pathways in muscle cells with control and precision. This will uncover new pathways that regulate muscle mass, insulin sensitivity, and mitochondrial function, leading to optimized therapies for age-related diseases, diabetes, and cancer, while reducing reliance on animal models.