Ultracentrifuge for native purification of biomolecules and vesicles
Name of applicant
Ebbe Sloth Andersen
Title
Associate Professor
Institution
Aarhus University
Amount
DKK 875,210
Year
2024
Type of grant
Research Infrastructure
Summary
Biological cells are used as factories to produce valuable biomolecules. Examples are proteins such as insulin, mRNA vaccines againts coronavirus, small molecule drugs, and membrane vesicles for drug delivery. An important step is to purify the valuable molecules from other cell components and here ultra-fast centrifugation is a core method that helps separation to obtain pure samples.