Purification of synthetic DNA/RNA-oligonucleotides
Navn på bevillingshaver
Poul Nielsen
Titel
Professor
Institution
University of Southern Denmark
Beløb
DKK 699,259
År
2023
Bevillingstype
Research Infrastructure
Resumé
Short DNA and RNA sequences called oligonucleotides form the basis for new therapeutics and nanomaterials. The technology relies on the synthesis and purification of tailored oligonucleotides that are chemically modified and/or conjugated to other entities. To achieve highly pure synthetic DNA/RNA oligonucleotides, a state-of-the-art analytical and preparative HPLC system is the precondition.